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PRODUCTS - Ursolic Plus

Composition :

URSODEOXYCHOLIC ACID 300mg and silymarin 150mg

Indication :
1.    Cholestatic Fatty Liver
2.    Non Alcoholic Steatohepatitis
3.    Intrahepatic Cholestasis in Pregnancy
4.    Chronic Hepatitis C
5.    Hepatocelular Carcinoma.

Dosage :
As per physician.
Contraindications :
Calcified & pigment gallstones, radio opaque gallstones. Non functioning gall bladders: chronic liver & peptic ulcer disease. Inflammatory disease of colon & small intestine. Pregnancy.
Precautions :
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter) medicines and herbal or vitamin supplements.
Mechanism Of Action :
URSOLIC  is a tertiary bile acid corrects immune abnormalities in liver and gall bladder as increases hepatic bile acid secretion and make more hydrophilic bile acids. Where hydrophobic bile acids are more damaging. Ursolic interact with hydrophobic bile acids and there by reduces their polarity and toxicity. It is the only drug approved by USFDA in the treatment of Hepato-biliary disorders that gives Protection of cholangiocytes (cells of gall bladder) against cytotoxicity of bile acids and hepatocytes against bile acid-induced apoptosis also stimulate  hepatobiliary secretion.
The preclinical studies using different hepatotoxic substances showed that silymarin has multiple actions as a hepatoprotective agent. The antioxidant property and cell-regenerating functions as a result of increased protein synthesis are considered as most important39. (i) Antioxidant properties: Free radicals, including the superoxide radical, hydroxyl radical (.OH), hydrogen peroxide (H2O2), and lipid peroxide radicals have been implicated in liver diseases.  Silymarin can also interact directly with cell membrane components to prevent any abnormalities in the content of lipid fraction responsible for maintaining normal fluidity22. (ii) Stimulation of protein synthesis:

DISCLAIMER : This product is available only in India against valid prescription from a Registered Medical Practitioner. This is not an offer for sale.