PRODUCT : STALFATE-O

CATEGORY :
ANTI-ULCERANTS
Composition :
Each 5ml : Sucralfate 1gm and Oxetacaine 10mg
Indication
It is used for the symptomatic treatment of ulcer & pain in Gastric Ulcer, Duodenal Ulcer, Gastritis, G.E.R.D
Class Of Drug
Anti Ulcerant
After oral administration, sucralfate reacts with hydrochloric acid in the stomach to form a paste-like complex that will bind to the proteinaceous exudates that generally are found at ulcer sites. This insoluble complex forms a barrier at the site and protects the ulcer from further damage caused by pepsin, acid or bile.
Dosage
1 TSF four times daily. Three times before meal and last dose at bed time.
Contraindications
Duodenal ulcer
Precautions
Renal impairement. Prolonged use. Hypophosphataemia. Actively bleeding ulcer. Exclude gastric malignancy before therapy. Pregnancy, lactation.
Mechanism Of Action
Stalfate is a locally acting substance that in an acidic environment (pH < 40) reacts with hydrochloric acid in the stomach to form a cross-linking, viscous, paste-like material capable of acting as an acid buffer for as long as 6 to 8 hours after a single dose. These complexes serve as protective barriers at the ulcer surface, preventing further damage from acid, pepsin, and bile.Stalfate also stimulates the increase of prostaglandin E2, epidermal growth factors(EGF), bFGF, and gastric mucus.
DISCLAIMER : This product is available only in India against valid prescription from a Registered Medical Practitioner. This is not an offer for sale.